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The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14.
Protein Sci. 2006 Oct;15(10):2423-34. doi: 10.1110/ps.062397806.
Protein Sci. 2006.
PMID: 17008723
Free PMC article.
MRG15 is a transcription factor expressed in a variety of human tissues, and its orthologs have been found in many other eukaryotes which constitute the MRG protein family. It plays a vital role in embryonic development and cell proliferation, and is involved in cel …
MRG15 is a transcription factor expressed in a variety of human tissues, and its orthologs have been found in many other eukaryotes w …
PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.
Tominaga K, Magee DM, Matzuk MM, Pereira-Smith OM.
Tominaga K, et al.
Mol Cell Biol. 2004 Oct;24(19):8366-73. doi: 10.1128/MCB.24.19.8366-8373.2004.
Mol Cell Biol. 2004.
PMID: 15367658
Free PMC article.
To elucidate the in vivo function of PAM14, we characterized the expression pattern of mouse Pam14 and generated PAM14-deficient (Pam14(-/-)) mice. Pam14 was widely expressed in all mouse tissues and as early as 7 days during embryonic development. Despite this ubiq …
To elucidate the in vivo function of PAM14, we characterized the expression pattern of mouse Pam14 and generated PAM14-deficient (Pam14(-/-) …
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